Peptide & Compound Research
Evidence-based profiles of peptides, metabolic compounds, and performance-enhancing substances with mechanisms of action, benefits, side effects, and dosing protocols.
Unlock detailed dosage protocols and compound profiles
Mechanism of Action
Binds to ghrelin receptors in the brain, causing sustained elevation of HGH and IGF-1 levels.
Benefits
- ✓Significant increase in HGH and IGF-1
- ✓Improved sleep quality
- ✓Enhanced recovery from training
- ✓Increased appetite (beneficial for bulking)
- ✓Oral administration (no injections)
- ✓Does not shut down natural HGH production
Side Effects
- •Water retention
- •Lethargy and fatigue
- •Increased appetite (can be negative)
- •Potential insulin resistance with long-term use
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Mechanism of Action
Promotes angiogenesis (new blood vessel formation) to accelerate healing in muscle, tendon, ligament, and gut tissue.
Benefits
- ✓Accelerates injury recovery
- ✓Reduces inflammation systemically
- ✓Heals gut lining (leaky gut)
- ✓Repairs tendons and ligaments
- ✓Improves overall tissue health
- ✓Can be injected near injury site for targeted repair
Side Effects
- •Minimal reported side effects
- •Generally well-tolerated
- •Long-term safety data limited
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Mechanism of Action
Promotes cell migration, tissue repair, and reduces inflammation throughout the body.
Benefits
- ✓Accelerates soft tissue healing
- ✓Reduces inflammation
- ✓Repairs muscle tears and tendonitis
- ✓Synergistic with BPC-157
- ✓Systemic healing effects
Side Effects
- •Minimal reported side effects
- •Generally safe
- •Limited long-term human data
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Mechanism of Action
Activates both GLP-1 and GIP receptors to drastically reduce appetite, slow gastric emptying, and improve metabolic function.
Benefits
- ✓Extremely effective for fat loss
- ✓Powerful appetite suppression
- ✓Improves insulin sensitivity
- ✓Slows gastric emptying (feel full longer)
- ✓Metabolic health benefits
Side Effects
- •Gastrointestinal issues (nausea, common)
- •Requires slow dose titration
- •Potential muscle loss if protein intake inadequate
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Mechanism of Action
Directly stimulates pituitary to release HGH in natural pulses, more biomimetic than MK-677.
Benefits
- ✓Natural pulsatile HGH release
- ✓Increases HGH and IGF-1
- ✓Cleaner than MK-677 (less water retention)
- ✓Synergistic with Ipamorelin
- ✓Improves recovery and growth
Side Effects
- •Minimal side effects
- •Requires injections
- •Generally well-tolerated
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Mechanism of Action
Long-acting IGF-1 variant that remains active much longer than natural IGF-1, creating pronounced anabolic effects.
Benefits
- ✓Powerful anabolic signaling
- ✓Promotes muscle hyperplasia (new cells)
- ✓Enhances hypertrophy (cell growth)
- ✓Synergistic with HGH secretagogues
- ✓Accelerated recovery
Side Effects
- •Potential insulin resistance
- •Hypoglycemia risk
- •Water retention
- •Nerve pain (carpal tunnel)
- •Requires careful dosing
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Mechanism of Action
Inhibits NNMT enzyme which normally depletes NAD+ and promotes fat storage. By blocking NNMT, cellular NAD+ levels increase, activating SIRT1 longevity genes, boosting cellular energy metabolism, and shrinking fat cells (adipocytes). Also increases SAM (S-adenosylmethionine) availability for DNA methylation.
Benefits
- ✓Potent fat loss through NNMT inhibition and adipocyte shrinkage
- ✓Increases cellular NAD+ levels naturally (synergistic with NAD+ supplementation)
- ✓Activates SIRT1 longevity pathway
- ✓Boosts basal metabolic rate and energy expenditure
- ✓May reverse diet-induced obesity
- ✓Improves cellular energy metabolism
- ✓Supports healthy DNA methylation patterns
- ✓Non-hormonal — suitable for both males and females
Side Effects
- •Limited human clinical data — primarily animal studies
- •Possible mild GI discomfort
- •Headache reported in some users
- •Unknown long-term safety profile
- •Expensive compared to other fat loss compounds
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Mechanism of Action
Stimulates the production of telomerase in somatic cells, which rebuilds and lengthens telomeres at the ends of chromosomes. This effectively reverses one of the primary mechanisms of cellular aging, allowing cells to continue dividing beyond their normal limit.
Benefits
- ✓Directly activates telomerase enzyme via TERT gene stimulation
- ✓Lengthens telomeres — reverses cellular aging clock
- ✓Improves sleep quality and circadian rhythm regulation
- ✓Enhances melatonin production in the pineal gland
- ✓Antioxidant properties — reduces lipid oxidation
- ✓May improve immune function and T-cell activity
- ✓Potential anti-cancer properties through normalized cell function
- ✓Shown to extend lifespan in animal studies by 13-30%
Side Effects
- •Generally well-tolerated with minimal reported side effects
- •Mild injection site irritation
- •Possible drowsiness due to melatonin regulation
- •Limited long-term human safety data
- •Theoretical concern about promoting cancer cell telomere growth (unproven)
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Mechanism of Action
Copper complex that stimulates collagen and elastin production, has antioxidant effects, promotes healing.
Benefits
- ✓Improves skin texture and firmness
- ✓Reduces fine lines and wrinkles
- ✓Supports hair follicle health
- ✓Anti-inflammatory effects
- ✓Wound healing
- ✓Systemic wellness benefits
Side Effects
- •Minimal reported
- •Generally very safe
- •Well-tolerated
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Mechanism of Action
IGF-1 variant released after muscle damage to signal satellite cells for local repair and growth.
Benefits
- ✓Localized muscle growth
- ✓Accelerated recovery
- ✓Can be injected into trained muscle
- ✓Amplifies natural repair process
- ✓Synergistic with systemic HGH
Side Effects
- •Minimal reported
- •Generally safe
- •Research-stage
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Mechanism of Action
Directly elevates GH levels, stimulating IGF-1 production in the liver. Promotes lipolysis, protein synthesis, and cellular repair.
Benefits
- ✓Powerful fat loss (especially visceral fat)
- ✓Improved skin quality and anti-aging
- ✓Enhanced recovery and healing
- ✓Better sleep quality
- ✓Increased muscle mass over time
- ✓Joint and connective tissue repair
- ✓Improved bone density
- ✓Cognitive benefits
Side Effects
- •Water retention and bloating
- •Carpal tunnel syndrome
- •Joint pain
- •Insulin resistance with high doses
- •Potential organ growth (acromegaly) with abuse
- •Expensive
- •Requires daily injections
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Latest Compound Research
Peer-reviewed findings, automatically curated and reviewed
BPC 157 was temporarily banned by WADA in 2022, signaling concerns about its use in sports and lack of regulatory approval for performance enhancement.
Preclinical research suggests BPC 157 has a good safety profile with few reported side effects, but it lacks human clinical trials for regulatory approval.
BPC 157 is not approved by the FDA or other regulators due to insufficient human clinical trials, despite its widespread use and online availability.
A new pilot study is underway to assess the safety of intravenous BPC-157 in humans, marking the first research into this administration method.
All findings are sourced from peer-reviewed literature and reviewed before publication.
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